Publications

2020 Posters

Following a decade of PCV in The Gambia should a decline in reistance be anticipated?

Predominance of clonal complex 320 among invasive Streptococcus pneumoniae serotyep 19F isolates from India in pre-vaccine era

Delineating the perturbation by PCV13 in composition of Streptococcus pneumoniae carriage isolates in Cambodia

Genetic diversity of cbpA among invasive Streptococcus pneumoniae isolates from India

Genetic variation associated with serotype 19A vaccine failures in Ireland

zmpB allelic variation in Streptococcus pneumoniae isolates causing meningitis in India population

Serotype, genotype and antibiotic resistance of non-vaccine type invasive pneumococcal isolates from pre-vaccine era (before 2018) - An Indian study

Global genomic epidemiology of pneumococcal serotype 2 isolated during 1989 to 2019

Molecular epidemiology of pneumococcus isolated from invasive pneumococcal diseases before introduction of PCV-10 in Bangladesh, 2002-2015

Acquisition and clearance of pneumococcal serotypes in naturally-colonised PCV-exposed Gambian infants

Antibiotic resistance patterns and phylogeography of Streptococcus pneumoniae associated with paediatric meningitis in pre- and post-PCV-introduction West and Central Africa

Spatial distance is a key determinant of pneumococcal strain sharing and the sustained carriage of shared strains

Genome analysis of invasive serotype 1 Streptococcus pneumoniae isolates from India

PCV10 impact on pneumococcal lineages isolated from healthy Nepalese children

Genome-wide association study of colonising nasopharyngeal pneumococci obtained from children in Nepal to identify genes associated with pneumonia

Genomics surveillance of invasive Streptococcus pneumoniae isolates (SPN) in Brazil, Periods pre- (2008-2009) and post-PCV10 (2012-2013) introduction

Population genetic structure, serotype distribution and antibiotic resistance of Streptococcus pneumoniae isolates collected in Moscow in 2011-2015

Streptococcus pneumoniae vaccine serotypes acquire penicillin binding protein gene mosaics from Streptococcus mitis

Genomics structure of invasive Streptococcus pneumoniae population from children under five years before and after vaccine introduction in Casablanca, Morocco.

2020 Journal Articles

Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation

A New Pneumococcal Capsule Type, 10D, is the 100th Serotype and Has a Large cps Fragment from an Oral Streptococcus

Visualising variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualise pneumococcal isolates

2019 Journal Articles

A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa

Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic data

Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study

Putative novel cps loci in a large global collection of pneumococci

International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact

2018 Journal Articles

Global distribution of invasive serotype 35D Streptococcus pneumoniae post-PCV13 introduction

Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci.

2018 Posters

Diversity of pneumococcal carriage in the Upper River Region of The Gambia in 2009 prior to the introduction of pneumococcal conjugate vaccines.

Molecular characterization of Streptococcus pneumoniae strains isolated from invasive disease in the pre- and post-PCV10 periods in Brazil, 2005-2015.

Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci.

Longitudinal surveillance reveals high clonality of pneumococcal carriage in the first year of life in The Gambia.

Genetic diversity and distribution of pneumococcal surface lipoproteins and implications on potential protein-based vaccines.

Population genomics reveals vaccination-induced genotypic changes in carried pneumococcal population.

Genetic diversity, serotype prediction and resistotyping of nasopharyngeal isolates of S. pneumoniae from Indian Hajj pilgrims by whole genome sequencing

Defining the lineages of the pneumococcus to understand disease and vaccine impact: a multi-continent genome analysis.

Hotspots of recombination in pneumococci isolated from nepalese children prior to PCV introduction

Insights into potential PCV effects on pneumococcal lineages using whole genome sequencing.

Comparative genomic analysis of samples collected pre- and post-introduction of pneumococcal conjugate vaccine (PCV7) in Hong Kong.

A multidrug resistant pneumococcal CC230 sub-lineage harbouring a mosaic tet(S/M) gene encoding tetracycline resistance in South Africa.

Whole genome sequencing of Streptococcus pneumoniae serogroup 19 isolates before the introduction of vaccine in the National Immunization Programme of India (NIP).

Indian population genomics datasets describing the pre-vaccine evolutionary epidemiology of Streptococcus pneumoniae using a whole genome sequencing approach.

Nasopharyngeal carriage of Streptococcus pneumoniae serotype 6A/6B in Gambian infants is highly dynamic within the first year of life: a longitudinal study.

Serotype diversity and putative novel cps loci in a large, global collection of pneumococci.

Invasive Streptococcus pneumoniae serotype 35B in South Africa, 2005-2016.

Antimicrobial resistance determinants and susceptibility profiles of pneumococcal carriage isolates recovered from healthy children in Peru pre-PCV introduction.

Antibiotic resistance of Streptococcus pneumoniae causing paediatric meningitis in west and central Africa, 2007-2016.

Population structure and erythromycin resistance of Streptococcus pneumoniae isolates collected in Moscow between 2011-2015.

Understanding the links between non-invasive and invasive pneumococci in children with severe pneumonia through comparative genomics.

Hospital based surveillance of vaccine preventable pneumococcal meningitis among children <=59 months in west and central Africa, 2010 to 2016.

Continued surveillance of invasive pneumococcal disease in African countries is needed to guide optimal vaccine design.

Impact of vaccination on nasopharyngeal carriage pneumococcal genotypic diversity among children in The Gambia: a longitudinal study.

Genomic epidemiology of Streptococcus pneumoniae serotype 5 pre and post introduction of PCV13 in The Gambia.

2017 Journal Articles

Antimicrobial resistance determinants and susceptibility profiles of pneumococcal isolates recovered from Trinidad and Tobago.

Key features of invasive pneumococcal isolates recovered in Lima, Peru determined through whole genome sequencing.

Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi.

2017 Posters

Rapid pneumococcal evolution in response to co-trimoxazole prophylaxis in a high-HIV burden population.

2016 Journal Articles

Phylogenetic analysis of invasive serotype 1 pneumococcus in South Africa, 1989 to 2013.

Detection of Streptococcus pneumoniae non vaccine serotype 12F clone 989 with acquired antibiotic resistance, circulating globally.

Detection of Streptococcus pneumoniae non vaccine serotype 12F clone 989 with acquired antibiotic resistance, circulating globally.